پديد آورنده :
طيراني نيك نژاد، احسان
عنوان :
الكترو ريسي و سنتز نانو الياف كيتوزان - پلي وينيل الكل به همراه نانو ذرات مغناطيسي آهن به منظور رهايش هدفمند پروتئين
مقطع تحصيلي :
كارشناسي ارشد
گرايش تحصيلي :
مهندسي شيمي
محل تحصيل :
اصفهان: دانشگاه صنعتي اصفهان، دانشكده مهندسي شيمي
صفحه شمار :
دوازده، 72ص.: مصور، جدول، نمودار
يادداشت :
ص.ع. به فارسي و انگليسي
استاد راهنما :
محمد قريشي، ندا حبيبي
توصيفگر ها :
نانو الياف پلي وينيل الكل-كيتوزان , رهايش هدفمند پروتئين آلبومين سرم گاوي , بار گذاري نانو ذرات مغناطيسي
تاريخ نمايه سازي :
28/2/94
استاد داور :
سعيد نوري خراساني، احمد اسدي نژاد
تاريخ ورود اطلاعات :
1396/09/27
رشته تحصيلي :
مهندسي شيمي
چكيده انگليسي :
Electrospun and Synthesis of chitosan Polyvinyl alcohol nanofibers with Fe3O4 magnetic nanoparticles for protein release Ehsan tayerani nick nejad e tayerani@ce iut ac ir Date of Submission 23 12 2014 Department of Chemical Engineerin Isfahan University of Technology Isfahan 84156 83111 Iran Degree M Sc Language FarsiSupervisors Seyyed Mohammad Ghoreishi ghoreshi@cc iut ac irNeda habibi n habibi@cc iut ac irAbstractOne of the important biomedical applications of nanotechnology currently being developed is drugrelease and drug delivery The use of nanotechnology in medicine offers some exciting possibilitiesinvolving drug delivery in which a certain dosage of drug is released in a targeted area over acertain period of time In this study we investigated the use of nanofibers in drug deliveryapplications Various polymers both of natural and of synthetic origin including chitosan andpolyvinyl alcohol PVA were used to obtain highly ordered nanofibers Nanofibers are widelyused in tissue engineering for development of nanofibrous scaffolds Tissue engineering is aninterdisciplinary field which seeks to close the gap between engineering and medical science Tissue engineering has created unique opportunity to fabricate tissues in the laboratory from acombination of cells and biologically active molecules Scaffolds that mimic the in vivoextracellular matrices play an important role in the field of tissue engineering In vivo extracellularmatrix components are in the nanometer scale Therefore nanofibrous scaffolds provide a betterenvironment in terms of cell adhesion proliferation and performance compared to traditionalscaffolds Here amongst the various methods electrospinning method was used for synthesis ofpolymer nanofibers In this method the nanofibers are generated by application of a strong electricfield over aluminum surfaces The shape and structure of nanofibers are influenced by processingparameters and solution properties such as viscosity surface tension dielectric constant conductivity concentration polymer molecular weight applied voltage flow rate distancebetween syringe and collector and syringe inner diameter Electrospinning is a straightforward andcost effective method of producing nanofibers from various natural and synthetic polymers Nanofibers have been used in diverse field such as tissue culture and drug delivery due to theirunique properties caused by high surface to volume ratio high porosity and small pores In thisstudy the morphology of the resultant nanofibers was studied by electron microscopy and the fiberthickness was estimated to be 60 200 nm It was found that the best fibers in terms of thickness and
استاد راهنما :
محمد قريشي، ندا حبيبي
استاد داور :
سعيد نوري خراساني، احمد اسدي نژاد
