پديد آورنده :
احمدي، تهمينه
عنوان :
بررسي ساخت و ارزيابي خواص غشاي نانو كامپوزيتي پلي كاپرولاكتون فورمات - ژلاتين - نانوذرات فلوئور آپاتيت ذوپ شده به وسيله سيليسيم و منيزيم جهت بازسازي بافت پريودنتال
محل تحصيل :
اصفهان، دانشگاه صنعتي اصفهان، دانشكده مهندسي مواد
صفحه شمار :
چهارده،130ص.: مصور
يادداشت :
با همكاري دانشگاه علوم پزشكي اصفهان
استاد راهنما :
احمد منشي، وجيه السادات مرتضوي
استاد مشاور :
محمدحسين فتحي، بتول هاشمي بني
توصيفگر ها :
فرآيند فعال سازي مكانيكي , الكتروريسي , غشاي پريودنتال
تاريخ نمايه سازي :
1394/11/07
استاد داور :
عليرضا خاوندي، محمد رضوي، رحمت اله عمادي
كد ايرانداك :
ID844 دكتري
چكيده انگليسي :
Investigating the manufacturing and evaluation of properties of nanocomposite membrane made of polycaprolactone fumarate gelatin flurapatite nanoparticle doped with silicon and magnesium for periodontal tissue regeneration Tahmineh Ahmadi t ahmadi@ma iut ac ir Date of Submission November 30 2015 Department of Materials Engineering Isfahan University of Technology Isfahan 84156 83111 Iran1st Supervisor Ahmad Monshi Professor monshi@cc iut ac ir2nd Supervisor Vajihesadat Mortazavi Professor Mortazaviva@yahoo com1st Advisor Mohammadhosein Fathi Professor Fathimh@ymail com2nd Advisor Batol Hashemibeni Associate Professor hashemibeni@med mui ac irDepartment Graduate Program Coordinator Dr Keyvan RaeissiAbstractThe aim of this study was to synthesize characterize and evaluate of nano compositemembrane of polycaprolactone fumarate gelatin silicon and magnesium co dopedfloroapatite for guided tissue regeneration of periodontal tissue The availablebiodegradable membranes degrade quickly before complete regeneration of tissue Forfabricating more suitable periodontal membrane which regenerates periodontal tissue andalveolar bone below procedure was done at the beginning flouroapatite was synthesized Then replacement of Magnesium instead of some Calcium and replacement of silicatebonds instead of some phosphate bonds were done There isn t any report about addition ofsilicon to apatite crystalline lattice by mechanical activation method and with cheap silica Silicon magnesium flourapatite nano particle was selected as the nano particle in thecomposite Polycaprolactone fumarate gelatin membrane was fabricated byelectrospinning method The manufactured polycaprolactone fumarate molecular weigth is10681 gr mol which is very low for electrospinning so gelatin with polycaprolactonefumarate was used After doing many tests and invatigating of different electrospinningparameters 30wt solution of polycaprolactone fumarate gelatin in acetic acid wasshaped by electrospinning method under below conditions 21 Kv voltage difference 15cm distance between syringe and collector Therafter 5 and 10 wt Silicon Magnesiumflourapatite nano particles were added to membrane and nano composite membranes weremade Nanoparticles had good distribution in polymer matrix Membrane with 5 wt nanoparticle had the best mechanichal properties between membrane with 10wt nanoparticle and membrane without nanoparticle Bioactivity and biodegradation of Department of Materials Engineering Isfahan University of Technology Isfahan 84156 83111 Iran Torabinejad Dental Research Center Department of Operative Dentistry School of Dentistry Isfahan University of Medical Sciences Isfahan 8174673461 Iran Research Group Department of Materials Engineering Isfahan University of Technology BiomaterialsIsfahan 8415683111 Iran Department of Anatomical Sciences and Molecular Biology School of Medicine Isfahan University ofMedical Sciences Isfahan 8174673461 Iran
استاد راهنما :
احمد منشي، وجيه السادات مرتضوي
استاد مشاور :
محمدحسين فتحي، بتول هاشمي بني
استاد داور :
عليرضا خاوندي، محمد رضوي، رحمت اله عمادي
