پديد آورنده :
مسعودپي، احسان
عنوان :
توسعه سيستم هاي ميكروسيالي به منظور بررسي تاثير گراديان شيميايي بر روي سلول هاي سرطاني
مقطع تحصيلي :
كارشناسي ارشد
گرايش تحصيلي :
ساخت و توليد
محل تحصيل :
اصفهان: دانشگاه صنعتي اصفهان، دانشكده مكانيك
صفحه شمار :
پانزده، 137ص.: مصور، جدول، عكس(رنگي)، نمودار
يادداشت :
ص. ع. به فارسي و انگليسي
استاد راهنما :
عليرضا فدائي تهراني
استاد مشاور :
امير صنعتي نژاد
توصيفگر ها :
ميكرو , نانو , ميكروسيال , درمان سرطان , پيشگيري از سرطان , گراديان شيميايي , آزمايشگاه بر روي تراشه , مهاجرت سلولي , سلول هاي بنيادي
استاد داور :
احسان فروزمهر، محسن ثقفيان
تاريخ ورود اطلاعات :
1396/05/01
چكيده انگليسي :
138 Development of Microfluidic Systems to Investigate the Effect of Chemical Gradient on Cancer Cells Ehsan Masoudpey e masoudpey@me iut ac ir Date of Submission 2017 06 21 Department of Mechanical Engineering Isfahan University of Technology Isfahan 84156 83111 Iran Degree M Sc Language FarsiSupervisor Dr Alireza Fadaei Tehrani mcjaft@cc iut ac irAbstract Due to the increase of various cancers among human societies and mortality during recent years different research groups have been working to prevent the growth of this phenomenon by using early andcheap detection techniques On the other hand further growth of modern science in interdisciplinary fields micro and nano scale and their importance in different fields and applications simplifying and performingcomplex experiments in microchips with high precision in the microfluidic field are helping in cancertreatment and prevention field Nowadays the invention of new and effective methods and existing method promotions aimed at thetreatment of cancer have been taken into consideration one of these methods is the study of circulatingtumor cells The importance of using these methods is the possibility of diagnosis in the early stages ofcancer timely prevention of cancer progression and appropriate treatment choice The main goal of thisthesis is simulation of cell culture medium in the microfluidic chips with cells microenvironment inchemical signaling field the chemical concentration gradient and observation cells migration behavior inthis field During this thesis initially all designed steps were performed to produce microstructure as amicrofluidic system then the effect of stem cell secretome on skin cancer was investigated Keywords Micro Nano Microfluidic Cancer treatment Cancer prevention Chemical gradient Labon a chip Cells migration Stem cells
استاد راهنما :
عليرضا فدائي تهراني
استاد مشاور :
امير صنعتي نژاد
استاد داور :
احسان فروزمهر، محسن ثقفيان
