14250

12896

كارشناسي ارشد

شيمي تجزيه

اصفهان : دانشگاه صنعتي اصفهان

1397

دوازده، ۴۴ص.: مصور، جدول، نمودار

محمد سراجي

بهزاد رضايي، محمدتقي جعفري

1397/10/26

كتابنامه

شيمي

شيمي

ID12896

Full evaporation technique combined with single drop microextraction for the determination of low molecular weight alcohols in biological fluids Javad Ghorbani j ghorbani1993@hotmail com Department of chemistry Isfahan University of Technology Isfahan 84156 83111 Iran Degree M Sc Language Farsi Supervisors Prof Mohammad SarajiAbstractIn this work for the first time full evaporation technique FE was combined with single dropmicroextraction for determining low molecular weight alcohols i e methanol ethanol andisopropanol in biological fluids In this technique a 80 L volume of sample was totallyevaporated inside of a sealed glass vial at 60 C Then the evaporated analytes were extracted intoa 2 L ethylene glycol droplet hanging from the tip of a microsyringe The important factorseffective on the extraction performance of the technique including extraction and evaporationtemperatures sample and solvent volumes and extraction time were studied The relative standarddeviation of the method was lower than 6 7 A good linearity r2 0 998 in the range of 0 03 7 00 0 03 10 0 and 0 03 10 0 mg L 1 was found for methanol ethanol and isopropanol respectively The limit of detection and quantification of the method were 0 01 and 0 03 mg L 1 respectively The method was successfully applied for the determination of the analytes in urine plasma and saliva samples The analyte recovery for the real samples was in the range of 82 100 Keywords Full evaporation Single drop microextraction Gas chromatography Biological fluids Alcohols

محمد سراجي

بهزاد رضايي، محمدتقي جعفري