پديد آورنده :
طالبي، عليرضا
عنوان :
ساخت و ارزيابي غشاهاي حاوي سلول بيوكامپوزيتي پلي كاپرولاكتون-كيتوزان-پلي پيرول- گرافن جهت كاربرد در مهندسي بافت قلب
مقطع تحصيلي :
كارشناسي ارشد
گرايش تحصيلي :
شناسايي و انتخاب و روش ساخت مواد
محل تحصيل :
اصفهان : دانشگاه صنعتي اصفهان
صفحه شمار :
نه، 65ص.: مصور، جدول، نمودار
استاد راهنما :
شيدا لباف، فتح اله كريم زاده
توصيفگر ها :
مهندسي بافت قلب , پلي كاپرولاكتون˛ پلي پيرول , كيتوزان , گرافن
استاد داور :
مهشيد خرازيها، عليرضا علافچيان
تاريخ ورود اطلاعات :
1398/01/25
تاريخ ويرايش اطلاعات :
1398/02/02
چكيده انگليسي :
66AbstractIn this study a novel polycaprolactone chitosan polypyrrole graphene PCL chitosan Ppy G conductive composite patch is fabricated For this purpose initially a polymer blend of PCL chitosan 7 3 was selected and then 1 2 5 5 and 7 5 wt of Ppywas added and also 0 5 1 5 and 2 5 wt of graphene COOH was added to each solution Arange of techniques were applied to study the chemical physical mechanical andantibacterial properties of the resultant films According to SEM images with the additionof Ppy and graphene to the PCL chitosan blend the size of the surface pits decreased and athigher concentration of Ppy porous structure is detected There was significant increase inthe electrical conductivity of the films such that the electrical conductivity of PCL chitosanwas 0 0164 0 008 mS m but increased to 0 55 0 03 mS m with the addition of 7 5 Ppyand for graphene contained samples increased to 5 3 0 16 S m with the addition of 2 5 G COOH Hydrophilicity was found to improve with the addition of G COOH as watercontact angle changed from 123 2 1 for PCL chitosan to 57 3 5 at 2 5 G COOH Themechanical properties of the scaffolds was shown to improve for example the tensilestrength increased from was 7 57 MPa for PCL chitosan sample to 18 06 16 02 15 33 and13 87 MPa for 1 2 5 5 and 7 5 wt Ppy and similarly for graphene contained fibrousscaffolds tensile strength increased from was 0 68 MPa for PCL chitosan sample to 0 83 4 56 and 2 75 MPa for 0 5 1 5 and 2 5 wt G COOH respectively The scaffolds containingPpy had improved antibacterial properties against E coli and S aureus The incorporationof Ppy and graphene within the PCL chitosan matrix was found to positively influence theoverall properties of scaffolds making them suitable for cardiac tissue engineeringapplications Keywords cardiac tissue engineering polypyrrole chitosan polycaprolactone graphene
استاد راهنما :
شيدا لباف، فتح اله كريم زاده
استاد داور :
مهشيد خرازيها، عليرضا علافچيان
