پديد آورنده :
صفري ، نرگس
عنوان :
ساخت و ارزيابي نانوكامپوزيت آنتي باكتريال تخريب پذير بر پايه منيزيم براي كاشتني هاي ارتوپدي
مقطع تحصيلي :
كارشناسي ارشد
گرايش تحصيلي :
شناسايي وانتخاب مواد
محل تحصيل :
اصفهان : دانشگاه صنعتي اصفهان
صفحه شمار :
شش ، 108 ص. : مصور، جدول، نمودار
استاد راهنما :
محمدرضا طرقي نژاد، مهشيد خرازيها
توصيفگر ها :
كاشتني هاي تخريب پذير استخواني , نانو كامپوزيت تخريب پذير , گرافن , آلياژهاي منيزيم , فرايند تف جوشي پلاسما جرقه اي
استاد داور :
شيدا لباف، مسعود عطاپور
تاريخ ورود اطلاعات :
1398/04/22
رشته تحصيلي :
مهندسي مواد
تاريخ ويرايش اطلاعات :
1398/04/22
چكيده انگليسي :
AbstractMillions of people suffer from bone diseases every year in the world In recent years implants havebeen developed to repair and fix bone fractures In this respect magnesium and its alloyspotentially be applied as degradable metallic materials in orthopedic implants due to theirdegradability and resemblance to human cortical bone However the high corrosion rate and weakmechanical properties of pure Mg hinders its clinical application Thus the alloys andnanocomposites of Mg developed to improve the mechanical and degradation properties Inflammation and infection at implants is another limitation of metallic implants in the humanbody For this reason the metallic implants with intrinsic antibacterial property introduced that thecopper and graphene nanoplates are the antibacterial property Therefore in this studybiodegradable and antibacterial Mg Al Cu Gr nanocomposite was developed using spark plasmasintering SPS approach for orthopedic applications In the first stage the Mg 1Al Cu alloyconsist of various amount of Cu 0 0 25 0 5 and 1 wt prepared For uniform distribution of Aland Cu in Mg matrix alloy the Al xCu x 20 33 and 50 wt powders fabricated by mechanicalalloying with difference time of milling 10 20 and 30 h After optimizing the time of milling theMg Al Cu alloys constructed by SPS method and evaluated via mechanical degradation biologicaland antibacterial properties The results shown with adding the 0 25 wt Cu in alloy the Al 2Cuintermetallic phase was distrusted uniformly compare to other alloys Specifically the compressivestrength and yield strength of pure Mg 167 MPa and 69 MPa respectively was significantlyenhanced to 232 MPa and 94 MPa respectively in Mg 1Al 0 25Cu alloy Noticeably incorporation of 0 25 wt Cu significantly improved degradation rate from 0 039 cm h in pure Mgto 0 00584 cm h in Mg 1Al 0 25Cu alloy Moreover the viability of MG63 cells in Mg 1Al 0 25Cu alloy promoted to 161 11 3 8 control compare to pure Mg 129 2 9 5 control Inaddition the antibacterial activity results of samples revealed that Mg Al Cu significantlyprevented from the growth of bacteria depending on the Cu content In the second stage the Mg 1Al 0 25Cu xGr x 0 18 and 0 5 wt nanocomposites fabricated via SPS method Though themechanical properties of Mg Al Cu Gr nanocomposite was not improved compare to Mg Al Cualloys the degradation rate of Mg 1Al Cu 0 18Gr decreased to 0 00133 cm h Also the viability of
استاد راهنما :
محمدرضا طرقي نژاد، مهشيد خرازيها
استاد داور :
شيدا لباف، مسعود عطاپور
