Abstract In this study, polycaprolactone-chitosan-diopside nanofibers were fabricated using electrospinning method and their performance for periodontal tissue was eva‎luated. Electrospinning factors such as changes in the amount of polymers and the addition of a diuretic ceramic site at 3, 5 to 7% by weight on the morphology of the fibers have been investigated.Electrospun nanofibers using scanning electron microscopy and X-ray diffraction analysis, analysis, infrared analysis, analysis, X-ray energy diffraction, tensile test, induction coupled plasma consumption analysis, cell culture analysis and toxicity. Bioactive and biodegradable have been studied Scanning electron microscopy images showed that smooth and uniform electrospinning fibers were optimal as scaffolds in samples containing 5% diopside ceramic with a distance of 25cm, a voltage of 15kV and a rate of 20 ml/h. Scanning electron microscopy analysis showed the structure of the fibers and the amount of change in fiber diameter by changing the percentage of diopside, and the results showed that the composite scaffold containing 5% ceramic diopside had more uniform fibers and less knots and willow.X-ray jump analysis examined the structure. Infrared experimental analysis confirmed the appropriate interaction between polymers and ceramics.The results of the X-ray diffraction measurement analysis eva‎luated the known elements in the samples. Bioactive and biodegradable analysis showed that the sample is approved for bio-applications.The results of induction coupling analysis showed that the amount of calcium and phosphate ions decreases with more passage due to the structure of hydroxyapatite on the fibers. The results of cell analysis and non-toxicity of cells showed high growth and proliferation of osteoblast cells on polycaprolactone-chitosan and diopside %5 scaffolds and this scaffold was a percentage for periodontal tissue function and bone formation.

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