Diabetes is generally described as a chronic, dangerous and progressive disease characterized by long-term metabolic disorders and high blood sugar, and in many cases, it brings irreversible complications. Therefore, the development of continuous- function glucose biosensors with high sensitivity, suitable selectivity, reliability, and low cost are necessary due to their potential applications in real-time prediction and detection of glucose fluctuations during the day. Now, the performance of biosensors especially depends on the structure of the working electrode. In this regard, it is first investigated that the use of transition group metals such as tungsten and molybdenum modified with noble metal nanoparticles can be a suitable alternative for the working electrode in continuous biosensors. Morphological and structural studies of the modified electrodes were carried out by scanning electron microscope and X-ray energy diffraction spectrometer, and then their mechanical properties were investigated. According to the microstructural and mechanical investigations, it was concluded that tungsten wire does not have a suitable capability for the working electrode of biosensors. In the next part, the electrochemical characteristics and ability to detect glucose were eva‎luated by cyclic voltammetry, amperometry and electrochemical impedance spectroscopy tests.

مسعود عطاپور , حميدرضا سليمي جزي

محمدمحسن مومني هامانه , عبدالمجيد اسلامي