سنتز و مشخصه‌يابي نانوكامپوزيت‌هاي بر پايه كربوكسي متيل سلولز با نانوذره‌هاي نقره اصلاح‌شده با ساكارز و بررسي ويژگي ضدباكتريايي آن‌ها

In this research, biocompatible nanocomposites based on carboxymethyl cellulose (CMC) with sucrose-modified silver nanoparticles were synthesized an‎d characterized. The synthesis of silver nanoparticles was carried out through a green method using sucrose as the reducing an‎d stabilizing agent, which resulted in the preparation of uniform an‎d stable particles. The obtained nanocomposite was formed by the uniform distribution of silver nanoparticles within the CMC matrix. Various techniques, including FTIR, X-ray diffraction (XRD), scanning electron microscopy (SEM), an‎d transmission electron microscopy (TEM), were employed to investigate the structure an‎d properties of these nanocomposites. The presence of sucrose as a stabilizing agent, in addition to preventing the aggregation of silver particles, enhances the biocompatibility an‎d preservation of these nanoparticles within the polymeric matrix. The antimicrobial activity of the samples against Gram-positive an‎d Gram-negative bacteria demonstrates the potential applications of these materials in medical fields, food packaging, an‎d water purification. The antibacterial mechanisms of silver nanoparticles include cell membrane disruption an‎d the generation of reactive oxygen species (ROS). This work highlights the key role of green methods in producing stable an‎d biocompatible nanocomposite materials, opening new horizons for nanotechnology applications across various industries.

غلامحسين محمدنژاد شيرازي

محمد ديناري , كاظم كرمي