پديد آورنده :
ضيايي راد، سپيده
عنوان :
سنتز، مكانيزم و مطالعات شيمي كوانتمي مشتقات جديد متيل ساليسيلات
مقطع تحصيلي :
كارشناسي ارشد
محل تحصيل :
اصفهان:دانشگاه صنعتي اصفهان، دانشكده شيمي
صفحه شمار :
چهارده،114،[II]ٌ ص:مصور،جدول،نمودار
يادداشت :
ص.ع.به فارسي و انگليسي
استاد راهنما :
عبدالحسين دباغ
توصيفگر ها :
واكنش كلب- اشميت , ساليسيليك اسيدها , هيدروكسي بنزوئيك اسيد , FT-IR , NMR , طيف سنجي
تاريخ نمايه سازي :
17/2/86
استاد داور :
عبدالرضا حاجي پور، حسين لقماني
چكيده فارسي :
به فارسي و انگليسي:قابل رويت در نسخه ديجيتالي
چكيده انگليسي :
Abstract Benzoic acid derivatives are important due to their pharmaceutical and biologicalactivities and their industrial applications The main derivatives of benzoic acid aresalicylic acid This compound and its derivatives are antiseptic and antipruritic drugs Hence one of the aims in this work is the synthesis and prepare the new derivatives of thesecompounds In this work we report the synthesis of several derivatives of methyl salycilate Methyl 2 4 dimethoxy salicylate 29 methyl 3 2 4 6 trimethoxy benzoate 40 andbis 2 4 6 trimethoxy phenyl methanone 41 by new method The Friedel crafts reaction ofelectronic rich 1 3 5 trimethoxy benzene 27 aluminum chloride as catalyses and methylchloroformate solvent with or without solvent and SiO2 produced adducts in good yields According to the resent advances in computational analysis promoted an investigationof intramolecular hydrogen bonding and conformational analysis of 29 and its derivatives 29b 29c and 29d by using the Hartree Fock HF and density functional methods Themolecular structure and geometry of methyl 2 4 dimethoxysalicylate 29 with itsderivatives 29b 29c 29d The FT IR vibration frequencies NBO values and 1H 13CNMR spectra of compound 29 were calculated in CDCl3 methanol DMSO d6 and invacuo using were exactly considered
استاد راهنما :
عبدالحسين دباغ
استاد داور :
عبدالرضا حاجي پور، حسين لقماني
