تهيه و مشخصه يابي پودر نانو متري فورستريت به روش آلياژ سازي مكانيكي و سل

چكيده انگليسي :

Fabrication and characterization of forsterite nanopowder by Mechanical Alloying and Sol Gel methods Mahshid Kharaziha kharaziha@ma iut ac ir Isfahan University of Technology Isfahan 84156 83111 IranDegree M Sc Language FarsiSupervisor M H Fathi fathi@cc iut ac ir AbstractAlthough hydroxyapatite is one of the most attractive bioceramic materials for human hard tissue implants replacing of bioceramics with good biocompatibility and better mechanical properties can dissolve theproblems of application in load bearing applications Resent results suggest that forsterite ceramic is abioceramic for biomedical application In addition nanometric forsterite can provide better biocompatibility In this study forsterite nanopowder and nanostructure forsterite bulk was prepared by mechanical alloyingand sol gel methods Forsterite powder was synthesized by mechanical alloying and post heat treatmentmethod using magnesium carbonate silica and ammonium hxafluorosilicate as a catalyst The effects of timeof mechanical alloying and heat treatment temperature on the phase structure and grain size of final powderwere studied Fabrication of forsterite by sol gel method was preformed by colloidal silica and magnesiumnitrate hexahydrate Sucrose and poly vinyl alcohol were used to fabricate a polymeric base to obtain pureforsterite at lower calcination temperature and time than the other sol gel methods The effects of calcinationtemperature and sucrose content on the phase structure grain size and morphology of forsterite powder werestudied Bioactive properties of forsterite nanopowder synthesized by two methods were studied byimmersing of the powder in the SBF In addition the in vitro biocompatibility of the forsterite nanopowderwas evaluated by osteoblasts adhesion and proliferation assay Forsterite dense bulk was prepared by twostep sintering method Hardness density and shrinkage of forsterite dense bulk were studied X raydiffraction XRD Thermal Gravity Analysis TGA Scanning Electron Microscopy SEM andTransmission Electron Microscopy TEM techniques were used to characterize and evaluate of the phasecomposition thermal behavior morphology and particle size of products Atomic Adsorption Spectroscopy AAS Fourier Transform Infra Red FTIR Spectrophotometer Energy Dispersive X ray EDX and SEMwere used to evaluating the bioactivity of forsterite nanopowder in the SBF It was found that pure forsteritenanopowder with grain size of 56 nm and particle size in the range of 35 60 nm was prepared by 10hmechanical alloying and 1h heat treatment at 1200 C In the presence of ammonium hxafluorosilicate pureforsterite powder with grain size of about 28 nm was synthesized by 5h mechanical alloying and 1h heattreatment at 900 C By Sol gel method forsterite nanopowder with grain size of 17 20 nm and particle sizeof 10 35 nm was prepared by 2h calcination at 800 C and sucrose to magnesium molar ratio of 4 1 Theresults of soaking of forsterite nanopowder on the SBF were shown forsterite nanopowder is bioactive Results of cell culture confirmed that the products from forsterite nanopowder dissolution significantlypromoted cell growth at a certain concentration range Furthermore osteoblasts adhered and spread well onthe nanostructure forsterite ceramics and osteoblasts proliferation on forsterite ceramics was obvious Forsterite dense bulk 98 1 0 22 TD with grain size of 65 70 nm was prepared from forsteritenanopowder synthesized by mechanical alloying by two step sintering Forsterite dense bulk 98 6 0 32 TD with grain size of 30 45 nm was prepared from forsterite nanopowder synthesized by sol gel method bytwo step sintering These findings suggest that forsterite nanostructure ceramics possess goodbiocompatibility bioactivity and mechanical properties and might be suitable for potential applications likeorthopedic and dental implant materials Key words Forsterite Nanostructure Mechanical Alloying Sol gel Bioactive

خرازيهاي اصفهاني، مهشيد

تهيه و مشخصه يابي پودر نانو متري فورستريت به روش آلياژ سازي مكانيكي و سل - ژل

نانو ساختار , زيست فعال , بيو سراميك ها , آزمون MTT