استخراج روغن بذرگل مغربي بادي اكسيد كربن فوق بحراني به روش نيمه پيوسته

چكيده انگليسي :

W K h Samaneh Khangholi Khangholi s@ce iut ac ir Submitted 6 May 2009 Department of Chemical Engineering Isfahan University of Technology Isfahan 84156 83111 Iran Assoc Prof Seyyed Mohammad Ghoreishi ghoreshi@cc iut ac ir Assist Prof Ali Akbar Dadkhah dadkhah@cc iut ac ir Abstract The oil obtained from Evening Primrose seeds is a source of linolenic GLA 18 3n 6 acid and therefore it enjoys widespread use in pharmacy and in the production of cosmetics Gamma linolenic acid is an important unsaturated fatty acid with active ingredients It is an essential acid for maintaining the normal physiological functions of the human body Gamma linolenic acid and its metabolite play an important and extensive physiological role in the immune system the cardio cerebral system and the endocrine system of the human body Gamma linolenic acid is an important intermediate in the human metabolic pathway that converts dietary linoleic acid LA into prostaglandins The bioconversion of linoleic acid to Gamma linolenic acid is catalyzed by the enzyme delta 6 desaturase but several factors including aging diabetes alcoholism atopic dermatitis rheumatoid arthritis cancer and cardiovascular disease can reduce or inhibit the activity of this enzyme leading to a variety of ailments Dietary supplementation of Gamma linolenic acid with naturally derived oils has been reported to be of value in treating several pathological conditions Gamma linolenic acid is found in human milk and in small amounts in a wide variety of common foods QRWDEO RUJDQ PHDWV W LV IRXQG LQ UHODWLYHO KLJK DEXQGDQFH LQ WKH SODQW VHHG RLOV RI HYHQLQJ SULPURVH J J $ EODFNFXUUDQW J J $ ERUDJH J J $ DQG IXQJDO RLO g 100 g GLA Although there are other sources of Gamma linolenic acid evening primrose oil appears to be the most biologically active The process of oil production especially conventional extraction methods can cause several chemical reactions in the oil components such as the degradation autooxidation and photooxidation of Gamma linolenic acid In this study supercritical fluid extraction SFE with carbon dioxide has been employed to recover evening primrose seed oil EPO The effective variables of temperature 33 61 C pressure 7 5 39 5 MPa static time period 5 45 min and dynamic time period 30 150 min were optimized by a factorial design method Extraction were performed with CO2 flow rate of 1 5 ml min and vessel was packed with 60 percent of crushed glass A partial factorial design was used to design the experiment and a mathematical model was constructed to relate the extraction yield to the variables The validity of the model was evaluated by analysis of variance ANOVA A second order polynomial equation is proposed for prediction of the extraction yields of evening primrose oil For the 99 confidence level p value must be less than 0 01 and is regarded as important variables for optimization of the experiment Nevertheless static time and the second order interactions are less important The adjusted correlation coefficient of the data R2 0 923 which indicates good performance of the model A recovery of 99 76 oil in the supercritical extract as compared to soxhlet was obtained in 27 min static time 123 min dynamic time a temperature of 44 C and a pressure of 35 7 MPa The EPO extracted via SFE in these extraction conditions had a light yellow color The experimental results indicate that EPO can be quickly and efficiently extracted via SFE at very mild conditions KEY WORDS Supercritical extraction carbon dioxide evening primrose oil linolenic acid factorial design method pdfMachine Is a pdf writer that produces quality PDF files with ease Produce quality PDF files in seconds and preserve the integrity of your original documents Compatible across nearly all Windows platforms if you can print from a windows application you can use pdfMachine Get yours now

خانقلي، سمانه

استخراج روغن بذرگل مغربي بادي اكسيد كربن فوق بحراني به روش نيمه پيوسته

گاما- لينولينك اسيد , طراحي فاكتوريل , سيالات فوق بحراني