5137

294 دكتري

دكتري

شيمي آلي

اصفهان: دانشگاه صنعتي اصفهان، دانشكده شيمي

1388

هفده، 155 ص.: مصور، جدول، نمودار

ص. ع. به فارسي و انگليسي

عبدالرضا حاجي پور

يوسف غايب

15/2/1389

امير عبدالملكي، ايرج محمد پور بلترك،‌ جواد صفايي قمي

شيمي

ID294 دكتري

به فارسي و انگليسي: قابل رؤيت در نسخه ديجيتال

Application of Potassium Iron Zirconium Phosphate and Zr HSO4 4 in the Friedel Crafts Alkylation and the Synthesis of Amino nitriles and Also the Application of the Acidic Ionic Liquid in the Synthesis of Some Organic Compounds Nafisehsadat Sheikhan NS Sheikhan@yahoo com Mar 8 2010 Department of chemistry Isfahan University of Technology 84156 83111 Isfahan Iran Supervisor Professor A R Hajipour Email haji@cc iut ac ir Advisor Assistant Professor Y Ghayeb Department Graduate Coordinator Professor B Najafi Isfahan University of Technology 84156 83111 Isfahan Iran Abstract In this investigation Potassium iron zirconium phosphate was used as a mild efficient and reusable solid acid catalyst for the Friedel Crafts alkylation of various arenes with benzyl bromide under solvent free conditions Also zirconium hydrogen sulfate as a mild solid acid catalyst was applied for the preparation of 6 amino nitriles from condensation of aldehydes or ketones with aniline and trimethylsilylcyanide under solvent free conditions at room temperature Br nsted acidic ionic liquids were designed to replace traditional mineral liquid acids in chemical procedures In this investigation N 4 sulfonic acid butyl triethyl ammonium hydrogen sulfate TEBSA HSO4 was synthesized and used as an efficient and reusable catalyst for the synthesis of some organic compounds A convenient mild and efficient procedure was reported for one pot three component synthesis of amidoalkyl naphthols derivatives from various aryl aldehydes 2 naphthol and different amides in the presence of TEBSA HSO4 under solvent free conditions at 120 C 14 aryl or alkyl 14H dibenzo a j xanthenes were prepared from one pot condensation of aldehydes with 2 naphthol using catalytic amount of Br nsted acidic ionic liquid under thermal solvent free conditions TEBSA HSO4 as effective catalyst was applied for the preparation of pyrimidinone derivatives from the reaction of aromatic aldehydes with cyclopentanone and urea or thiourea under thermal solvent free conditions Finally TEBSA HSO4 catalyzed the Pechmann condensation of various phenols with different D ketoesters leading to the formation of coumarins under solvent free conditions Key Words Friedel Crafts Br nsted acidic ionic liquid Amidoalkyl naphthols Pyrimidinone Coumarins 6 Amino nitriles 1 Introduction Replacing strong mineral acid homogeneous corrosive and polluting catalysts with heterogeneous eco friendly solid acid catalysts in producing of various fine chemicals has been attracted many interest Solid acids have many advantages such as easy handling decreasing reactor and plant corrosion problem and environmentally safe disposal over conventional mineral acids Thus we found that potassium iron zirconium phosphate PIZP and zirconium hydrogen sulfate can be used as efficient and heterogeneous solid acids for Friedel Crafts alkylation and the synthesis of 6 amino nitriles under solvent free conditions Recently ionic liquids ILs as useful green solvents or catalysts have been applied in many reactions Sahoo et al 2006 and Forbes et al 2004 due to their specific properties such as undetectable vapor pressure non inflammability wide liquid range reusability and high thermal stability Welton et al 1999 and

عبدالرضا حاجي پور

يوسف غايب

امير عبدالملكي، ايرج محمد پور بلترك،‌ جواد صفايي قمي