5476

5136

كارشناسي ارشد

شناسايي و انتخاب مواد

اصفهان: دانشگاه صنعتي اصفهان، دانشكده مواد

1389

ده،99ص.: مصور،جدول،نمودار

ص.ع.به فارسي و انگليسي

محمد حسين فتحي

24/7/89

حسين ادريس، محمدرضا سائري

مهندسي مواد

ID5136

به فارسي و انگليسي: قابل رويت در نسخه ديجيتالي

Fabrication and Characterization of Magnesium Fluoridated Hydroxyapatite Nanopowder and Nanostructured coating via sol gel route Mehdi Kheradmandfard Email address Mkh fard@yahoo com Date of Submission April 13 2010 Department of Materials Engineering Isfahan University of Technology Isfahan 84156 83111 Iran Degree M Sc Language Farsi Supervisor s Name Mohammad Hossein Fathi Professor fathi@cc iut ac ir Abstract Biological apatites contain many substitutions i e F CO32 Na Mg 2 Zn 2 Properties of hydroxyapatite HA or fluorapatite FA such as bioactivity biocompatibility solubility and adsorption properties can be tailored over a wide range by modifying the composition via ionic substitutions The aim of this work was preparation and characterization of Mg doped FA Mg FA nanopowders Mg FA nanopowders with different Mg content were prepared by sol gel method The designated degree of substitution of Ca2 by Mg2 in the mixture was indicated by the x value in the general formula of Ca10 xMgx PO4 6F2 where x 0 0 25 0 5 0 75 and 1 Mg FA nanopowders with different Mg content were also prepared by mechanical alloying MA method The designated degree of substitution of Ca2 by Mg2 in the mixture was indicated by the x value in the general formula of Ca10 xMgx PO4 6F2 where x 0 0 5 1 1 5 and 2 X ray diffraction XRD scanning electron microscopic SEM atomic absorption spectrophotometer AAS Fourier transform infrared spectroscopy FTIR and transmission electron microscopy TEM techniques were utilized to characterize the obtained powders In vitro bioactivity evaluation of powders were investigated by soaking the powders in simulated body fluid SBF for predicted various time periods in order to analyze the nucleation and growth of bone like apatite carbonate containing hydroxyapatite on the surface of the powders FTIR SEM and AAS techniques were utilized to identify and characterize the formed bone like apatite on the obtained powders Results indicated that Mg ions entered into the fluorapatite lattice and occupied Ca2 sites and obtained powders had crystallite size about 30 100 nm With increasing the Mg substitution the solubility of powders and the adsorption of Ca2 ions onto the powders surfaces increased simultaneously It was concluded that Mg substitution improves the bioactivity of FA and the bioactivity is proportional to Mg concentration of powders Keywords Nanostructured Hydroxyapatite Fluor Magnesium Bioactivity Sol gel processes

محمد حسين فتحي

حسين ادريس، محمدرضا سائري