7104

6632

كارشناسي ارشد

تكنولوژي نساجي

اصفهان: دانشگاه صنعتي اصفهان، دانشكده نساجي

1390

شانزده، 140ص.: مصور، جدول، نمودار

ص.ع. به فارسي و انگليسي

داريوش سمناني

شهناز رضوي

29/7/91

محمد ذره بيني، لاله قاسمي

1396/09/20

كتابنامه

نساجي

مهندسي نساجي

ID6632

به فارسي و انگليسي: قابل رويت در نسخه ديجيتالي

Simulating and Investigating the Mechanical and the Surface Properties ofArtificial Esophagus Made from Weft Knitted Fabric Coated by Nanofibers Amin Zadbagher Seyghalani a zadbagherseyghalani@tx iut ac ir Date of Submission March 10 2012 Department of Textile Engineering Isfahan University of Technology Isfahan 84156 83111 IranDegree M Sc Language FarsiDariosh Semnani d semnani@cc iut ac irAbstractEsophagus is a tubular shaped muscle mucous tissue that connect the mouth and throat to the stomach Todays inmany countries a lot of diseases caused by defects of esophagus Esophageal tissue engineering scaffolds canmake a suitable solution in surgical treat esophagus defects Extensive mechanical studies on esophagus haveshown that it is a highly elastic tissue exhibiting anisotropic behavior High elasticity and porous structure ofweft knitted fabrics make them applicable for the tissue engineering scaffolds Because of high porosity of theweft knitted fabrics uniform growth of cells on the scaffolds is not possible Therefore in addition to themechanical properties of fabric parameters it is necessary to investigate other parameters of optimum scaffold Inthis study plain tubular weft knitted fabric has been used as a scaffold of esophagus tissue engineering Tosimulate esophagus tissue engineering scaffold the fabric samples have been made in tubular shape withPolyglycolicAcid PGA yarn on V bed machine The physical properties of weft knitted fabric scaffold wasinvestigated to find usability of fabric as esophagus prothesis The fabric characterization and optimumconditions for production of textiles were experienced Mechanical tests on fabrics with specific applications arenot affordable so the computer model for simulating weft knitted esophagus scaffold was applied This fabric wasmodeled in two dimensional condition The behavior of scaffold has been analyzed in the Abaqus software According to the non linear characteristics of the weft knitted fabric and esophageal tissue hyperelastic form hasbeen used as material definition Hyperelasticity is the capability of a material to experience large elastic straindue to small forces without losing its original properties Experimental data of fabric scaffolds were comparedwith mathematics and the finite element method The behavior of scaffolds has been investigation by applyinguniaxial tension in longitudinal and width directions After that flowing food through the esophagus scaffold fortissue engineering was modeled by finite element methods Comparison the actual data presented a goodperformance of the model To decrease porosity of scaffold polycaprolacton nanofibers coated PGA fabric Afterthat gelatin solution coated composite of fabrics and nanofibers to prepare scaffold for cell culture This surfacemodification significantly improved initial cells adhesion and proliferation Adding the gelatin to the surfaceincreased roughness and decreased porosity of scaffold whereas evaluation of surface morphology is animportant factor for cell attachment on scaffolds image processing technique has been applied to determinesurface roughness of scaffolds The results of scaffold surface roughness presented that the surface of scaffoldwas suitable for cell growing Keyword Tissue engineering Uniaxial tensile force Weft knitted loop Analytical and Finite element methodsimulation Electrospinning Image processing

داريوش سمناني

شهناز رضوي

محمد ذره بيني، لاله قاسمي