7704

7176

كارشناسي ارشد

شيمي معدني

اصفهان: دانشگاه صنعتي اصفهان، دانشكده شيمي

1391

يازده،113ص.: مصور،جدول،نمودار

ص.ع.به فارسي و انگليسي

حسن حدادزاده

شادپور ملك پور

17/2/92

حسن قاضي عسگر، كاظم كرمي

شيمي

ID7176

به فارسي و انگليسي: قابل رويت در نسخه ديجيتالي

The mononuclear complexes of Co II and Zn II with meloxicam synthesis characterization crystal structures and DNA binding studies Separation of selenium from the Sarcheshmeh copper anode slimes and optimization process without any degradation in the nature of gold and silver metals Tahereh Hosseinzadeh Sanatkar t hoseinzadesanatkar@ch iut ac ir Date of Submission 2013 01 14 Department of Chemistry Isfahan University of Technology Isfahan 84156 83111 Iran Degree M Sc Language Farsi Supervisor Hassan Hadadzadeh hadad@cc iut ac ir Abstract This thesis contains two parts In the first part two mononuclear complexes of the meloxicam Co Hmel 2 EtOH 2 and Zn Hmel 2 EtOH 2 have been synthesized and characterized by elemental analysis FT IR and UV Vis spectroscopy Solid state structures of the complexes were determined by single crystal X ray diffraction In the complexes the two meloxicam act as monoanionic bidentate ligands that coordinated to the metal center through the nitrogen atoms from the thiazole rings and the amide oxygen atoms In the complexes a strong intramolecular hydrogen bond between the amide N H function and the enolate O atom stabilized the ZZZ conformation of the meloxicam ligands In addition the complexes have a distorted octahedral geometry and the bond lengths of apical positions are elongated than the equatorial positions In this work the binding behaviors of the complexes with FS DNA were also investigated by UV Vis and fluorescence spectroscopy and cyclic voltammetry Hyperchromism and blue shift were observed in the absorption spectral titration of the complexes with FS DNA which indicated the complexes bind to the DNA The intrinsic binding constant Kb was obtained from absorption spectral titration For both complexes the results indicate that the complexes can interact with FS DNA through an electrostatic mode In the second part the separation of selenium from the Sarcheshmeh copper anode slimes and the optimization of this process were reported Anode slimes refer to the undissolved materials that deposit on the bottom of the electrolytic cells during the refining of copper Anode slimes contain precious metals such as Au Ag Se and Te and other metals like Fe Cu and Ni The previous works for anode slimes processing were based on pyrometallurgical methods These methods were performed in high temperature and produced toxic gases that cause environmental pollution and reduce the recovery of metals This present work a combination of pyrometallurgical and hydrometallurgical treatment of anode slimes is suggested to achieve the selective and complete recovery of selenium At first an alkaline roasting of anode slimes turns selenium contents into selenate and selenite forms After of leaching and filtration of the samples the solutions were analyzed by atomic absorption spectroscopy AAS Then the selenium was deposited with the reducing agents Na2SO3 The effect of temperature time and amount of reagents were also studied for determination of the optimum conditions of roasting The optimum conditions are as follow temperature 600 C time 6 h and Na2CO3 slime ratio 0 5 By these conditions 99 47 of Se was separated from anode slimes Key word Meloxicam complexes DNA binding Anode slime Roasting process

حسن حدادزاده

شادپور ملك پور

حسن قاضي عسگر، كاظم كرمي