عنوان :
ساخت و مشخصه يابي داربست نانو ليفي جهت دار پلي ﴿گليسرول سباكيت﴾ براي كاربرد مهندسي بافت قرينه چشم
محل تحصيل :
اصفهان: دانشگاه صنعتي اصفهان، دانشكده مواد
صفحه شمار :
دوازده،153ص.: مصور،جدول،نمودار
يادداشت :
ص.ع.به فارسي و انگليسي
استاد راهنما :
محمد حسين فتحي، شقايق حق جوي جوانمرد
استاد مشاور :
سعيد نوري خراساني
توصيفگر ها :
الكتروريسي , نانو الياف , زيست سازگاري
تاريخ نمايه سازي :
14/8/92
استاد داور :
محمد مرداني، حسين ادريس، داريوش سمناني
كد ايرانداك :
ID577 دكتري
چكيده فارسي :
به فارسي و انگليسي: قابل رويت در نسخه ديجيتالي
چكيده انگليسي :
Fabrication and characterization of aligned nanofibrous scaffolds of poly glycerol sebacate for cornea tissue engineering Sahar Salehi E mail address Salehi@ma iut ac ir Date of submission 25 08 2013 Department of materials engineering Isfahan University of Technology Isfahan 8415683111 Iran Supervisor Prof M H Fathi fathi@cc iut ac ir Co Supervisor Prof Sh Haghjooyjavanmard shaghayeghhaghjoo@yahoo com Advisor Prof S NouriKhorasani saied@cc iut ac ir Department Graduate Program Coordinator Keyvan Raeissi Biomaterials Research Group Department of Materials Engineering Isfahan University of Technology 8415683111 Isfahan Iran Physiology Research Center Department of Physiology Isfahan University of Medical Sciences 8174673461 Isfahan Iran Department of chemistry Engineering Isfahan University of Technology 8415683111 Isfahan Iran Abstract Morphological studies of aligned nanofibers scaffolds made of poly glycerol sebacate PGS poly e caprolactone PCL blends for application as corneal tissue scaffolds are presented Parallel conductive bars are used as ground electrode to generate unidirectional nanofibers Scaffolds have fibers diameter in the range of 550 300 nm The structural stability and wettability especially the in vitro degradation rate of the electrospun scaffolds can be controlled by regulating the blended ratio of the polymers Composition 4 1 showed the best cell viability in contact to endothelium and epithelium cells All of the compositions were inert in contact to the lymphocytes The results indicate that PGS PCL nanofiber scaffolds can be considered as ideal candidates for corneal tissue engineering scaffolds The particular motivation for this work is to engineer a tissue like construct that will mimic the stromal tissue of the cornea Keywords Tissue engineering Electrospinning Poly glycerol sebacte Poly caprolactone Polycondensation Cornea Aligned naofibers
استاد راهنما :
محمد حسين فتحي، شقايق حق جوي جوانمرد
استاد مشاور :
سعيد نوري خراساني
استاد داور :
محمد مرداني، حسين ادريس، داريوش سمناني
