8445

7826

كارشناسي ارشد

شيمي تجزيه

اصفهان: دانشگاه صنعتي اصفهان، دانشكده شيمي

1392

دوازده،53ص.: مصور،جدول،نمودار

ص.ع.به فارسي و انگليسي

بهزاد رضايي

علي اصغر انصافي

1/11/92

كيومرث زرگوش، محمد ژياني

شيمي

ID7826

به فارسي و انگليسي: قابل رويت در نسخه ديجيتالي

Application of Nanoparticles and Moleculary Imprinted Polymer as Modifier for Fabrication of Electrochemical Sensor for Determination of Trace Amounts of Morphine Shervin Foroughi Dehnavi shervin foroughi@yahoo com September 22 2013 Department of Chemistry Isfahan University of Technology Isfahan 84156 83111 Iran Degree M Sc Lanquage Farsi Supervisers Professor Behzad Rezaei E mail rezaei@cc iut ac ir Advisor Professor Ali A Ensafi E mail ensafi@cc iut ac ir Abstract In this context a simple and rapid method for trace amounts of morphine detection has been described based on electrochemical methods of pencil graphite electrode PGE which was constructed by using Multi wall carbon nanotubes MWCNT molecularly imprinted polymer MIP and gold nanoparticles In the electropolymerization process selective MIP was produced using Methyltrimethoxysilane and Tetraethylorthosilicate as monomer and cross linker respectively on modified electrode in NaOH solution The structural morphology of the modified electrode was characterized by field emission scanning electron microscopy FE SEM technique Various types of electrochemical methods containing cyclic voltammetry CV square wave voltammetry SWV and electrochemical impedance spectroscopy EIS were employed to probe the characteristics of the constructed electrode toward morphine After optimization of several effective parameters the calibration curve was obtained by SWV which increased linearly dependent on the MO 1 concentration over the range of 0 008 to 0 1 and 0 1 to 5 in two linear fragments vs Ag AgCl The sensitivity for morphine detection was improved greatly and the detection limit was 2 85 nM The relative 1 standard deviation RSD for six replicate determinations of 0 05 morphine was found to be 5 46 S N 6 Finally the ability of the electrochemical sensor was successfully applied for determination of target in real samples such as human urine and plasma that was succeeded with satisfactory results The results indicated that the proposed electrode exhibited high sensitivity and stability for detecting morphine Keywords Morphine Electrochemical Sensor Voltammetric method Nano particels Multiwall carbon nanotubes Au nanoparticles Molecularly imprinted polymer Pencil graphite electrode PDF created with pdfFactory trial version www pdffactory com

بهزاد رضايي

علي اصغر انصافي

كيومرث زرگوش، محمد ژياني