Author :
Hajipour, A. R.,Pyne, Stephen G
Title of Article :
unexpected rearrangement of a B-amino sulfoxide under pummerer reaction conditions
Title Of Periodical :
TETRAHEDRON
VolumNumber :
V.50, No.47
Descriptors :
Chiral sulfoxide,Bezazepine alkaloide,Pummerer rearrangment
Abstract :
Attempts to prepare the benzazepine ring system of the Rhoedine alkaloids using a pummerer cyclization of the B-amino sulfoxide (16) gave instead the unexpected alcohol (19). The B-amino sulfoxide (16) was prepared via a diastereoselective reduction of the B-sulfinyl enamine (8) with sodium borohydride.
