پديد آورنده :
حاجي زاده، سارا
عنوان :
مطالعه تاثير ديازپام و گياه مورت بر روي الگوي خواب موش هاي صحرائي
مقطع تحصيلي :
كارشناسي ارشد
محل تحصيل :
اصفهان: دانشگاه صنعتي اصفهان، دانشكده فيزيك
صفحه شمار :
سيزده، ۵۸ص.: مصور، جدول، نمودار
استاد راهنما :
فرهاد شهبازي، مرضيه زارع
استاد مشاور :
كيوان آقابابايي ساماني
توصيفگر ها :
ديازپام , مورت , خوابREM , طيف توان - فركانس , طيف تكينگي , نماي هارست , چرخه خواب , الگوريتم پيگيري تطبيقي
استاد داور :
ممتحن داخلي: جواد هاشمي فر، فرهاد فضيله
تاريخ ورود اطلاعات :
1397/04/27
چكيده انگليسي :
Studying the effect of Diazepam and Myrtus on rats sleep patterns Sara Hajizadeh s hajizadeh@ph iut ac ir March 7 2018 Department of Physics Isfahan University of Technology Isfahan 84156 83111 Iran University Code IUT 77142 Degree M S c Language Farsi supervisors Dr F Shahbazi Dr M Zare shahbazi@cc iut ac ir marziehzare@ipm ir Abstract Diazepam is a medication of the benzodiazepine family commonly used to treat sleep disorders insomnia and to reduce tension or anxiety It is on the World Health Organization s List of Essential Medicines as one of the most effective and safe medicines needed in a health system However some side effects of benzodiazepines such as diazepam are anterograde amnesia confusion especially in high doses and sedation Moreover Diazepam reduces slow wave and REM sleep and also leads to sleep latency reduction Medicinal plants have also been used for treating sleep disorders and insomnia Myrtus communis for instance is recommended by Ethiopian traditional medicine and aromatherapy for reliving insomnia It prolongs sleep duration and reduces sleep latency This study examines the effect of diazepam and Myrtus on sleep cycle memory correlation and long range correlation Experiments were carried out on 12 male Wistar rats of weight 295 320 g which were divided into three groups control diazepam and myrtus groups Two electrodes were implanted in the area between the neck muscle and occipital bone to record Electromyography EMG activity Differential recordings from the two electrodes located in the lateral parietal and lateral occipital cortices were used to record slow wave and spindle neocortical EEG activity This experiment has been done by Dr Feizi in Shahid Beheshti university medical faculty The power frequency spectrum distribution Using the algorithm matching pursuit Husrt exponents and singularity spectrum are compared between the groups Results of examining sleep cycle and power frequency spectrum show reduction of REM sleep and high frequency bands for both diazepam and myrtus groups In fractal analysis parameters Diazepam however leads to fewer changes in dynamic features of sleep in comparison with myrtus Keywords Diazepam Myrtus REM sleep power frequency spectrum distribution sleep cycle Husrtexponent singularity spectrum matching pursuit
استاد راهنما :
فرهاد شهبازي، مرضيه زارع
استاد مشاور :
كيوان آقابابايي ساماني
استاد داور :
ممتحن داخلي: جواد هاشمي فر، فرهاد فضيله
