پديد آورنده :
ستايش نسب، حامد
عنوان :
مدل‌سازي احتمالاتي رفتار بيومكانيكي بافت قرنيه به‌منظور مطالعه فشار داخلي چشم
مقطع تحصيلي :
كارشناسي ارشد
گرايش تحصيلي :
طراحي كاربردي
محل تحصيل :
اصفهان : دانشگاه صنعتي اصفهان
صفحه شمار :
پانزده، 121ص.: مصور، جدول، نمودار
استاد راهنما :
محمود كدخدائي، پيمان مصدق
استاد مشاور :
محمد سيلاني، وحيد يعقوبي
توصيفگر ها :
فشار درون‌چشمي , فشارسنجي , تونومتر كرويس , قرنيه , لنز تماسي , مدل‌سازي تصادفي , تحليل حساسيت
استاد داور :
محمد مشايخي، مهدي جوانبخت
تاريخ ورود اطلاعات :
1398/04/07
رشته تحصيلي :
مهندسي مكانيك
تاريخ ويرايش اطلاعات :
1398/04/12
چكيده انگليسي :
122 Probabilistic Modeling of Biomechanical Behavior of the Cornea to Study the Intraocular Pressure Hamed Setayeshnasab h setayeshnasab@me iut ac ir June 15 2019 Department of Mechanical Engineering Isfahan University of Technology Isfahan 84156 83111 IranDegree Master of Science Language PersianSupervisors Mahmoud Kadkhodaei Prof kadkhodaei@cc iut ac ir Peiman Mosaddegh Assoc Prof mosadegh@cc iut ac ir AbstractVision is a vitally important sense therefore it is essential to study and evaluate the eye in order topredict and treat the related diseases For this reason researchers and engineers have always designedmany devices in order to recognize the structure and behavior of the eye and have modeled differentparts of the eye in order to better predict and understand it The Intraocular Pressure is also one ofthe most important factors affecting the eyesight and therefore its value should always be within aspecified range But the estimated pressure by these devices is not sufficiently precise and isdependent on various factors including material properties thickness curvature and boundaryconditions of the cornea The purpose of this study was to investigate corneal biomechanical behaviorin response to the Corvis tonometer to correct the pressure estimation by considering the affectingfactors To this end the tonometry test was simulated for a contact lens with predefined geometry properties internal pressure and boundary conditions Then in a variety of internal pressures geometries and properties the relationship between the applied internal pressure and the parametersreported by the tonometer was studied then the effect of inputs on these parameters was evaluated Subsequently finite element simulations were converted to surrogate models using stochasticmodeling theory Using these models the Corvis parameters were calculated in a fraction of a second and analysis of these parameters introduced suitable indicators for diagnosis and medical prognosis Afterward with a reverse trick the surrogate models were used and the applied internal pressure wasextracted as a black box function of other factors In this way for each contact lens the true internalpressure and the pressure reported by Corvis ST will be comparable and correctable This processprovides a novel and quick way for IOP measurement to ophthalmologists At the end of thisresearch by performing a suitable statistical sensitivity analysis the effect of factors such asthickness curvature and material properties on the Corvis parameters was studied and similarly theeffect of all parameters on the IOP estimation process was investigated This analysis showed that for more accurate measurement of the applied internal pressure the deflection amplitude the radiusof curvature and the applanation time should be measured with a higher accuracy The deflectionamplitude is also influenced by the radius of curvature and thickness and the applanation timedepends on the central thickness and the material model respectively KeywordsIntraocular Pressure IOP estimation Corvis ST Cornea Contact lens Stochastic modeling Sensitivity analysis
استاد راهنما :
محمود كدخدائي، پيمان مصدق
استاد مشاور :
محمد سيلاني، وحيد يعقوبي
استاد داور :
محمد مشايخي، مهدي جوانبخت
