In this thesis, an electrochemical sensor was prepared using glassy carbon electrode modified with composite including multi-walled carbon nanotubes, zinc oxide, cerium oxide and ionic liquid to measure acetaminophen. Synthesis proof and morphology studies of the synthesized compounds were done using energy dispersive X-ray spectroscopic analysis, X-ray diffraction pattern and scanning electron microscope. In addition, the behavior of the used electrocatalyst was eva‎luated by differential pulse voltammetry and electrochemical impedance spectroscopy methods. After optimizing all factors affecting the sensor response, a linear range of 0.1 µM to 200 μM was obtained with the detection limit 0.0097 μM in the measurement of acetaminophen. Finally, after investigating the selectivity of the method in the presence of some potential interfering species, the f-MWCNT/ZnO@CeO2/GCE sensor was successfully used to measure acetaminophen in the tissue of real human blood plasma samples and commercial tablet samples.

بهزاد رضايي

علي اصغر انصافي

محمدتقي جعفري، اسماعيل حيدري