پديد آورنده :
رزاقي ،فاطمه
عنوان :
بررسي بيو شيميايي و هيستو پاتولوژيك قلب جوجه هاي كوشتي در سندرم آسيت در مناطق هم سطح دريا و مرتفع
مقطع تحصيلي :
كارشناسي ارشد
محل تحصيل :
اصفهان: دانشگاه صنعتي اصفهان، دانشكده كشاورزي
صفحه شمار :
نه ،61،[II]ص،مصور ،جدول ،نمودار
يادداشت :
ص.ع به:فارسي وانگليسي
استاد راهنما :
نفيسه نيلي
استاد مشاور :
محمد رضا رحماني ،عبدالكريم زماني
توصيفگر ها :
ژلاتين زايموگرافي
تاريخ نمايه سازي :
18/1/87
استاد داور :
مهدي محمد عليپور، مهدي كديور
چكيده فارسي :
به فارسي و انگليسي :قابل رويت در نسخه ديجيتال
چكيده انگليسي :
Abstract Increasing world population and vital need for protein sources demands selectiontechniques for fast growing broilers to meet human needs However growth ofimportant organs of these broilers does not match their growth rate High growth rateincreases metabolic activities and oxygen requirements that can lead to increasedmetabolic disorder Since lungs can not provide enough oxygen for metabolic needs ofthese chickens hypoxia occurs specially at high altitude and ascites syndrome canoccur This syndrome can cause significant economic loss to poultry industry The aimof this study was to investigate cellular and molecular mechanisms of ascites syndrome Heart samples were taken at weeks 2 3 4 5 and 6 from 20 male broilers Ross 308 that were kept at two different districts of sea level Rasht and 2150 meter above sea Shahrekord In Shahrekord food restriction was exerted at week 4 Morphological andhistopathological analysis H E staining collagen content measurements OH prolinemeasurement and MMP level evaluation gelatin zymography were performed Statistical analysis was carried out by GLM procedure from SAS In Shahrekord sbroilers hypoxia caused increased MMP 2 levels in right ventricle wall that resulted inECM degradation and heart remodeling that was evident in histological analysis Also there was a higher right ventricle volume in Shahrekord s samples as compared to thatof Rasht At week 4 there was lower levels of active MMP 2 in Shahrekord s samplesthat was followed by a significant increase in collagen content could be due to feedrestriction at this week Although broilers in Shahrekord district had a healthyappearance low oxygen pressure had significant effect at cellular molecular levels However by reversing these effects food restriction may have controlled onset ofascites syndrome in Shahrekord s broilers
استاد راهنما :
نفيسه نيلي
استاد مشاور :
محمد رضا رحماني ،عبدالكريم زماني
استاد داور :
مهدي محمد عليپور، مهدي كديور
