4414

4163

كارشناسي ارشد

شيمي

اصفهان: دانشگاه صنعتي اصفهان، دانشكده شيمي

1387

چهارده ،105،[II]ص،مصور ،جدول،نمودار

ص.ع به : فارسي و انگليسي

عبدالرضا حاجي پور

18/1/88

مجيدمير محمد صادقي ،امير عبدالملكي

1396/09/11

كتابنامه

شيمي

ID4163

به فارسي و انگليسي :قابل رويت در نسخه ديجيتال

Abstract Ionic Liquids ILs have been frequently used as a green solvent in place of classicalorganic solvents in modern synthetic chemistry due to their reduced pollution low cost andstraightforward work up The application of ILs as solvent and catalyst has reported for a variety of functional grouptransformation Ionic liquids usually possess unique properties such as non volatility non flammability and low melting point negligible vapor pressure and talent to dissolve manyorganic and inorganic compounds Recently ILs have been successfully employed as dual reagent solvents catalytic for avariety of reactions but their use as catalyst under solvent free conditions need to be givenmore attention In recent years many types of reactions have been investigated in IL therefore here in ourcontinuation for developing green methods in organic synthesis we wish to report thesynthesize and characterization of morpholinium chloride as a novel ionic liquid and itsapplication in some organic reactions Protected hydroxyl functionalities are very important intermediates due to their organicand analytical chemistry Many multi step syntheses in organic reactions include at leastone step of alcohol group protection In this regard one of the most common strategies isto convert alcohols into their corresponding tetrahydropyranyl THP ethers The THPethers are attractive because their straightforward preparation and less expensive and alsostability under different conditions such as strong basic media Grignard reagents andorganometallic reagents In this project a mild procedure for protection of alcohols with 3 4 dihydro 2H pyran atroom temperature in the presence IL under solvent free condition has been investigated Organic halides are talent intermediates in organic synthesis They react with nucleophiles such as amines or alkoxides to give the corresponding substituted products They are oftenused for in C C bond formation via radical or substitution reactions Although alkyl chlorides are often used but alkyl chlorides are less reactive than alkylbromides or iodides Thus an efficient and practical protocol for the preparation of alkylbromides also has been studied employing this ionic Liquid Oxidation is a fundamental transformation in organic synthesis and there are numerousmethods reported in the literature Potassium permanganate KMnO4 has been used as anoxidant Here also we in oxidation of primary and secondary benzylic alcohols wereconverted to their corresponding carbonyl compound by using KMnO4 in the presence ofmorpholinium chloride as IL in acetonitrile under refluxing conditions The projects have several major advantages such as using inexpensive material mildreaction conditions short reaction times and good to high yields Key words ionic liquids oxidation of alcohols bromination of alcohols protection ofalcohols

عبدالرضا حاجي پور

مجيدمير محمد صادقي ،امير عبدالملكي