پديد آورنده :
حيدرخان تهراني، اشكان
عنوان :
ساخت داربست نانو كامپوزيتي پلي هيدروكسي بوتيرات / هيدروكسي آپاتيت به روش الكتروريسي و به منظور استفاده در مهندسي بافت
مقطع تحصيلي :
كارشناسي ارشد
گرايش تحصيلي :
شيمي نساجي و علوم الياف
محل تحصيل :
اصفهان: دانشگاه صنعتي اصفهان، دانشكده نساجي
صفحه شمار :
سيزده،95ص.:مصور،جدول،نمودار
يادداشت :
ص.ع.به فارسي و انگليسي
استاد راهنما :
علي زادهوش،سعيد كرباسي
استاد مشاور :
سعيد نوري خراساني
توصيفگر ها :
داربست نانو اليافي , شبيه سازي كامپيوتري , پردازش تصويري , تخلخل , طراحي تاگوچي , كشت سلولي
تاريخ نمايه سازي :
17/5/89
استاد داور :
محمد مرشد،محمد رفيعي نيا
چكيده فارسي :
به فارسي و انگليسي: قابل رويت در نسخه ديجيتالي
چكيده انگليسي :
Fabricating Electrospun Poly 3 hydroxybutyrate Hydroxyapatite Nanocomposite Scaffold for Tissue Engineering Application Ashkan Heidarkhan Tehrani a htehrani@tx iut ac ir 05th May 2010 Department of Textile Engineering Isfahan University of Technology Isfahan 84156 83111 IranDegree M Sc Language PersianAli Zadhoush zadhoush@cc iut ac irSaeed Karbasi Karbasi@med mui ac irAbstractIn this dissertation the three dimensional structure of the electrospun fibrous scaffold was simulatedusing an image modeling technique Fabricating Poly 3 hydroxybutyrate scaffolds according to aTaguchi experimental design both the processing parameters as injection Flow rate applied voltageand nozzle collector distance and the material parameters as the Polymer concentration volatility andconductivity of the solution were investigated having assessed the scaffolds architecturalcharacteristics as the porosity pores numbers pores size pores interconnectivity and webspermeability indices WPI all the control parameters were then optimized The applicability of aunique deduced criterion called Scaffolds Percolative Efficiency SPE was validated with the invitro culture of mouse fibroblast cells on the structurally distinguished scaffolds The structurallyoptimized scaffold matrix was then reinforced with up to 15 wt natural Hydroxyapatitenanoparticles Mechanical and physical properties of the resulted Bio Nanocomposite scaffolds werecharacterized with the help of tensile test and FTIR spectrophotometer and scanning electronmicroscopy with which the most desired mechanical and bioactivity properties was obtained when upto 8 wt of Hydroxyapatite nanoparticles was present Keyword Nanofibrous Scaffold Biopolymer Computer Simulation Image Processing PoreInterconnectivity Taguchi Design in Vitro Cell Culture
استاد راهنما :
علي زادهوش،سعيد كرباسي
استاد مشاور :
سعيد نوري خراساني
استاد داور :
محمد مرشد،محمد رفيعي نيا
