پديد آورنده :
نظام الديني، محمد
عنوان :
ساخت سنسور الكتروشيميايي بر پايه الكترود مداد كربن اصلاح شده با پليمر حكاكي شده مولكولي جهت اندازه گيري مقادير كم فوروزمايد
مقطع تحصيلي :
كارشناسي ارشد
گرايش تحصيلي :
شيمي تجزيه
محل تحصيل :
اصفهان: دانشگاه صنعتي اصفهان، دانشكده شيمي
صفحه شمار :
سيزده،51ص.: مصور،جدول،نمودار
يادداشت :
ص.ع.به فارسي و انگليسي
استاد راهنما :
بهزاد رضايي
استاد مشاور :
علي اصغر انصافي
توصيفگر ها :
حسگر الكتروشيميايي , نانو لوله هاي كربني چند ديواره
تاريخ نمايه سازي :
20/1/92
استاد داور :
تقي خياميان، محمدتقي جعفري
چكيده فارسي :
به فارسي و انگليسي: قابل رويت در نسخه ديجيتالي
چكيده انگليسي :
Construction of electrochemical sensor based on pencil graphite electrode modified with molecularly imprinted polymer for sensitive determination of furosemide Seyed Mohammad Nezamoddini mnezamodin@yahoo com December 10 2012 Department of Chemistry Isfahan University of Technology Isfahan 84156 83111 Iran Degree M Sc Lanquage Farsi E mail rezaei@cc iut ac ir Supervisers Professor Behzad Rezaei E mail ensafi@cc iut ac ir Advisor Professor Ali A Ensafi Abstract A novel and simple electrochemical sensor is constructed for selective determination of furosemide by combination of a multi wall carbon nanotube MWCNT layer with a thin molecularly imprinted polymer MIP film The sensor is fabricated onto pencil graphite electrode PGE via stepwise modification of MWCNT and a thin polymer film of molecularly imprinted polymers by using electrodeposition method The molecularly imprinted film displayed excellent selectivity towards furosemide Due to such combination the sensor responded quickly to furosemide The morphology and performance of the sensor is characterized by cyclic voltammetry CV square wave voltammetry SWV and electrochemical impedance spectroscopy EIS The interaction between the imprinted sensor and target molecule is observed by measuring the variation of current response of the oxidation reduction of the K3Fe CN 6 as a probe on electrode Under the optimal experimental conditions the response peak current is linear to the concentration of furosemide in the range from 0 08 to 4 00 PM and the detection limit is 35 nM This imprinted sensor is successfully tested to the determination of furosemide in human urine samples These results revealed that the imprinted sensor fulfilled the selectivity sensitivity speed and simplicity requirements for furosemide detection and provided possibilities of clinical application in physiological fluids Keywords Molecularly imprinted polymer Electrochemical sensor Pencil graphite electrode Multi walled carbon nanotubes furosemide
استاد راهنما :
بهزاد رضايي
استاد مشاور :
علي اصغر انصافي
استاد داور :
تقي خياميان، محمدتقي جعفري
